About 2,260,000 results
Open links in new tab
  1. About Sickle Cell Disease | Sickle Cell Disease (SCD) | CDC

    Feb 21, 2025 · People with SCD may start to have signs of the disease during the first year of life, usually around 5 months of age. Symptoms and complications of SCD are different for each person …

  2. Sickle cell disease - Wikipedia

    In sickle cell disease, low oxygen tension promotes red blood cell sickling and repeated episodes of sickling damage the cell membrane and decrease the cell's elasticity.

  3. Sickle Cell Disease (SCD) Symptoms, Causes & Types

    Sickle cell disease (SCD) is an inherited blood disorder. It causes your red blood cells to form into a “C” shape. It can cause pain and serious complications.

  4. Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow causing lifelong …

  5. Sickle Cell Disease - Johns Hopkins Medicine

    Sickle cell disease is a blood disorder in which the hemoglobin is damaged and can't carry oxygen to the tissues. These blood cells with the defective hemoglobin are sticky and can build up and block small …

  6. Sickle cell anemia - Symptoms & causes - Mayo Clinic

    Sickle cell anemia is one of a group of inherited disorders known as sickle cell disease. It affects the shape of red blood cells, which carry oxygen to all parts of the body. Red blood cells are usually …

  7. Sickle-cell disease - World Health Organization (WHO)

    Aug 6, 2025 · Sickle-cell disease is a serious inherited blood disorder caused by a mutation in the HBB gene, leading to abnormal, sickle-shaped red blood cells that block blood flow and cause severe …

  8. Sickle Cell Disease | FDA

    Healthy red blood cells are flexible and travel through your blood vessels to carry oxygen to your tissues. Sickle cell disease (SCD) is caused by a genetic mutation that changes the shape of...

  9. Sickle Cell Anemia: Genetics, Chronic Symptoms, Support

    4 days ago · Sickle cell disease is an inherited condition that affects the oxygen-carrying hemoglobin protein in red blood cells. It carries a risk of a sickle cell crisis, pain, infections, and blood clots. The …

  10. Sickle Cell Disease (SCD) | Sickle Cell Disease (SCD) | CDC

    Featured Data and Statistics Find sickle cell disease-related data and statistics on prevalence, complications, and more.